If symptoms occur or persist, obtain medical attention. The department of labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. Safety data sheet msds is obtained unless a current one is already. Identification of the substancemixture and of the companyundertaking 1. Show this safety data sheet to the doctor in attendance. Take necessary action to avoid static electricity discharge which might cause ignition of organic vapors. The occupational safety and health administrations osha hazard communication standard 29 cfr 1910. Page 1 of 8 msds chloroform material safety data sheet msds chloroform 1. Safety data sheet a university in missouri, college in. Safety data sheet according to 29cfr19101200 and ghs rev. Physical and chemical properties molecular formula chcl3. Phosgene may form in the head space in chloroform containers. It can harm the eyes, skin, liver, kidneys, and nervous system. Chloroform was traditionally made from acetone and bleaching powder, but is now created from the photochemical reaction of.
Francisco as a result of a phenolchloroform laboratory accident. Chloroform will not be expected to bioconcentrate into the food chain but contamination of food is likely due to its use as an extractant and its presence in drinking water. Chloroform trichloromethane, cas 67663 ghs chemical container label. The level of exposure depends upon the dose, duration, and work being done. Due to its light sensitivity, it may undergo degradation with time. However, we make no warranty of merchantibility or any other warranty, express or. Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. There have been a number of phenol splashes to the face that have occurred at cornell. Phenol has an anesthetic effect and can cause severe burns that may not be immediately painful or visible. For specific material handling data sheets referen ces, contact cornell corporation. Birth defects have been seen in rats and mice exposed by inhalation of chloroform at concentrations greater than 100 ppm in air.
Chloroform chcl3 is a colorless liquid that quickly evaporates into gas. Handling, storage and safety please use this guide in conjunction with this products country specific safety data sheet sds and the safe use conditions as described therein. Individuals are exposed to volatile compounds present in tap water by ingestion, inhalation, and dermal absorption. Always check your browsers address bar before you enter your netid password to make sure the address starts with where web is either web1, web2, web3 or web4. As in any fire, always wear selfcontained breathing apparatus in pressuredemand msaniosh approved or equivalent, and full protective gear. The information above is believed to be accurate and represents the best information currently available to us. Hplc grade product number 270636 brand aldrich company sigmaaldrich. Material safety data sheet msds chloroform click here to download pdf datasheet welcome to our online chloroform shop buy online or call us on. If seeking medical attention provide sds document to physician.
As the conditions or methods of use are beyond our control, we do not assume any responsibility and. May react with combustible substances creating fire or explosion hazard and formation of toxic fumes. Chloroform 270636 anonymousanonymous 602006004 67663 1. Ingestion, inhalation, and dermal exposures to chloroform. Product and company identification product name chloroform, stabilized with ethanol. Tested to withstand exposure to acetone, dichloromethane, hydrofluoric acid, and other tough chemicals and solvents. Evaluation and optimization of dna extraction and purification. Chloroform 67663 98 100% all concentrations are percent by weight unless ingredient is a gas. Soil, sand, vermiculite for disposal by an approved method. These sdss are designed to provide essential information. For operations involving the use of larger amounts of chloroform, such as transferring. Methanol safety data sheet according to federal register vol. The threshold concentration of human skin damage from phenol is 1.
Chloroform safety data sheet according to federal register vol. Other information the information presented above is offered for informational purposes only. This can be suppressed by adding ethanol as a stabilizer. Cornell campus police 911 accidents, spills environmental health and safety 58200 gannett health center 55155 12. This sds, and the associated product, is intended for use only by technically qualified. Chloroform a3 group 2b reasonably anticipated x not listed ethyl alcohol not listed group 1 not listed x not listed acgih. Osha occupational chemical database occupational safety. This material safety data sheet was prepared to comply with the osha hazard communication standard 29 cfr 1910.
Preparation and clearing of bacterial lysate the qiaprep miniprep procedure uses the modified alkaline lysis method of birnboim and doly 2. Risk of kidney and liver damage through inhalation. Chloroform chcl 3, cas 67663, also called trichloromethane, is a clear, dense, colorless, and nonflammable liquid with a pleasant odor sweet in taste and insoluble in water, chloroform dissolves easily in alcohol, acetone, gasoline, and other organic solvents. Endangers drinkingwater supplies if allowed to enter soil. May decompose into toxic and corrosive gases hydrogen chloride, phosgene, chlorine, carbon monoxide and carbon dioxide under fire conditions. Cuweblogin is a component of cornell universitys central authentication service. Toxicological information vapor lc50 inhalation vapor rat 47702 mgm.
Dependable 3m adhesive vinyl that is built to resist harsh conditions. In order for infotrac to provide coverage, your material must be on the sds list. Safety data sheets sdss environmental health and safety. If you are unsure of the authenticity of any online university. The use of chloroform in cosmetic products is prohibited because it causes cancer. All steps are performed without the use of phenol, chloroform, cscl, ethidium bromide, and without alcohol precipitation. This list of hazardous materials totals over chemicals and is updated as needed. First aid measures general advice move out of dangerous area.
Chemical product and company identification product name. Specifications, hplc grade the gr is an emd trademark and indicates this chemical reagent is suitable for use in analytical chemistry and that the product meets or exceeds american chem. To maintain this coverage cornell provides infotrac with sds information for all hazardous materials shipped. Cornell corporation uses a variety of raw material suppliers to manufactureassemble the finished products, which the above information was obtained. Thank you for visiting our website you are exiting the department of labors web server. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Sds or msds of constituents, or product name and manufacturer. Acetone revision date 25apr2019 skin contact wash off immediately with plenty of water for at least 15 minutes. The addition will increase the polarity of the solvent. P271 use only outdoors or in a wellventilated area. Special precautions, incompatiblereactive materials, usable shelf life, etc. P270 do not eat, drink or smoke when using this product. Regulatory information osha hazards target organ effect, harmful by ingestion.
Bead mill homogenization in a lysis mixture containing chloroform, sds, nacl, and phosphatetris buffer ph 8. Weill cornell medicine research, clinical, service, maintenance, and cleaning operations generate several types of waste chemical, biological, radioactive, universal, and recyclable. Ingestion of chloroform by pregnant laboratory animals has resulted in fetotoxicity but not birth defects, and only at levels causing severe maternal effects. May cause damage to the liver or kidneys through prolonged or repeated inhalation. Suspected of damaging fertility or the unborn child. Ingestion of chloroform by pregnant laboratory animals has resulted in. Durable laminate that increases the label strength and resistance. If inhaled if breathed in, move person into fresh air. Sigmaaldrich material safety data sheet date printed.
Traditional risk assessments for water often only consider ingestion exposure to toxic chemicals, even though showering has been shown to increase the body burden of certain chemicals due to inhalation exposure and dermal absorption. Developing a written hazardous waste disposal manual and an. Stop and contain the spill for salvage or absorb in inert absorbent material e. However, we make no warranty of merchantability or any other warranty, express or implied. Rinse immediately with plenty of water for at least 5 minutes while lifting the eye lids. Waste must be adequately managed by personnel generators in their work areas prior to collection andor disposal. Bacteria are lysed under alkaline conditions, and the lysate is subse. Vapour has anaesthetic properties, causing drowsiness, intoxication, nausea, vomiting, unconsciousness. The perfect tool for accomplishing this feat is the material safety data sheet msds. Check availability and compare product details chloroform contains 100200 ppm amylenes as stabilizer. Sigmaaldrich offers a number of chloroform products.
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